Reaction Details Report a problem with these data
Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM97226
Substrate
n/a
IC50
>833.93±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM97226
Synonyms:
MLS001018585 | N-[4-(trifluoromethylsulfanyl)phenyl]pyridine-2-carboxamide | N-[4-(trifluoromethylthio)phenyl]-2-pyridinecarboxamide | N-[4-(trifluoromethylthio)phenyl]picolinamide | SMR000354860 | cid_2302878
Type:
Small organic molecule
Emp. Form.:
C13H9F3N2OS
Mol. Mass.:
298.284
SMILES:
FC(F)(F)Sc1ccc(NC(=O)c2ccccn2)cc1
Structure:
Search PDB for entries with ligand similarity: