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Target
Nuclear receptor subfamily 0 group B member 1
Ligand
BDBM97228
Substrate
n/a
IC50
>833.93±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay (2013)[AID] 
Target
Name:
Nuclear receptor subfamily 0 group B member 1
Synonyms:
AHC | DAX1 | NR0B1 | NR0B1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
51729.22
Organism:
Homo sapiens (Human)
Description:
gi_5016090
Residue:
470
Sequence:
MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNVALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGLPGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQRPGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSSGALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELAQDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQAIKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQGPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
  
Inhibitor
Name:
BDBM97228
Synonyms:
(2-methoxyphenyl)-[5-(tetrahydropyran-2-ylmethylthio)-1,3,4-thiadiazol-2-yl]amine | MLS001007629 | N-(2-methoxyphenyl)-5-(2-oxanylmethylthio)-1,3,4-thiadiazol-2-amine | N-(2-methoxyphenyl)-5-(oxan-2-ylmethylsulfanyl)-1,3,4-thiadiazol-2-amine | SMR000384825 | cid_16196311
Type:
Small organic molecule
Emp. Form.:
C15H19N3O2S2
Mol. Mass.:
337.46
SMILES:
COc1ccccc1Nc1nnc(SCC2CCCCO2)s1
Structure:
Search PDB for entries with ligand similarity: