Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM49483
Substrate
n/a
IC50
>67488±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay PubChem Bioassay (2013)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM49483
Synonyms:
5-[(1,3-benzoxazol-2-ylhydrazinylidene)methyl]-2-methoxy-phenol | 5-[(1,3-benzoxazol-2-ylhydrazinylidene)methyl]-2-methoxyphenol | 5-[(1,3-benzoxazol-2-ylhydrazono)methyl]-2-methoxy-phenol | 5-[(E)-(1,3-benzoxazol-2-ylhydrazono)methyl]-2-methoxy-phenol | MLS000536056 | SMR000155368 | cid_3938498
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3
Mol. Mass.:
283.282
SMILES:
COc1ccc(CN=Nc2nc3ccccc3o2)cc1O |w:8.8|
Structure:
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