Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM97201
Substrate
n/a
IC50
>67500±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay PubChem Bioassay (2013)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM97201
Synonyms:
3-(4,5,6,7-Tetrahydro-benzothiazol-2-yl)-chromen-2-one | 3-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)-1-benzopyran-2-one | 3-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)chromen-2-one | 3-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)coumarin | MLS000566484 | SMR000177435 | cid_846394
Type:
Small organic molecule
Emp. Form.:
C16H13NO2S
Mol. Mass.:
283.345
SMILES:
O=c1oc2ccccc2cc1-c1nc2CCCCc2s1
Structure:
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