Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM93823
Substrate
n/a
IC50
>67490±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay PubChem Bioassay (2013)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM93823
Synonyms:
(E)-3-(4-methylanilino)-1-thiophen-2-yl-2-propen-1-one | (E)-3-(4-methylanilino)-1-thiophen-2-ylprop-2-en-1-one | (E)-3-(p-toluidino)-1-(2-thienyl)prop-2-en-1-one | (E)-3-[(4-methylphenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one | 3-[(4-methylphenyl)amino]-1-(2-thienyl)-2-propen-1-one | MLS000671966 | SMR000294473 | cid_2210959
Type:
Small organic molecule
Emp. Form.:
C14H13NOS
Mol. Mass.:
243.324
SMILES:
Cc1ccc(cc1)N=CCC(=O)c1cccs1 |w:7.7|
Structure:
Search PDB for entries with ligand similarity: