Reaction Details Report a problem with these data
Target
Steroidogenic factor 1
Ligand
BDBM97323
Substrate
n/a
IC50
>67482±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): Luminescence-based cell-based high throughput dose response assay for nonselective inhibitors/assay artifacts using AP2 mutant SF-1 (NR5A1) Transactivation Assay PubChem Bioassay (2013)[AID] 
Target
Name:
Steroidogenic factor 1
Synonyms:
AD4BP | Adrenal 4-binding protein | FTZF1 | Fushi tarazu factor homolog 1 | NR5A1 | Nuclear receptor subfamily 5 group A member 1 | SF-1 | SF1 | STF-1 | STF1_HUMAN | Steroid hormone receptor Ad4BP
Type:
Nuclear Hormone Receptor
Mol. Mass.:
51643.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
461
Sequence:
MDYSYDEDLDELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKHYTCTESQSCKIDKTQRKRCPFCRFQKCLTVGMRLEAVRADRMRGGRNKFGPMYKRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLAAGPPAGPLGDFGAPALPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEPYASPPQPGLPYGYPEPFSGGPNVPELILQLLQLEPDEDQVRARILGCLQEPTKSRPDQPAAFGLLCRMADQTFISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQAKQT
  
Inhibitor
Name:
BDBM97323
Synonyms:
1-(2-phenylethyl)-3-(2-pyrimidinyl)thiourea | 1-(2-phenylethyl)-3-pyrimidin-2-yl-thiourea | 1-(2-phenylethyl)-3-pyrimidin-2-ylthiourea | 1-phenethyl-3-(2-pyrimidyl)thiourea | MLS002638918 | SMR001548380 | cid_4557737
Type:
Small organic molecule
Emp. Form.:
C13H14N4S
Mol. Mass.:
258.342
SMILES:
S=C(NCCc1ccccc1)Nc1ncccn1
Structure:
Search PDB for entries with ligand similarity: