Reaction Details Report a problem with these data
Target
Kallikrein-7
Ligand
BDBM100005
Substrate
n/a
EC50
8334±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100005
Synonyms:
1-(9-methoxy-5H-pyrimid[5,4-b]indol-4-yl)isonipecotic acid ethyl ester | 1-(9-methoxy-5H-pyrimido[5,4-b]indol-4-yl)-4-piperidinecarboxylic acid ethyl ester | MLS000040611 | SMR000045614 | cid_664591 | ethyl 1-(9-methoxy-5H-pyrimido[5,4-b]indol-4-yl)piperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C19H22N4O3
Mol. Mass.:
354.403
SMILES:
CCOC(=O)C1CCN(CC1)c1ncnc2c1[nH]c1cccc(OC)c21
Structure:
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