Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM42042
Substrate
n/a
IC50
2272±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM42042
Synonyms:
4-Ethoxy-N-pyridin-4-ylmethyl-benzenesulfonamide | 4-ethoxy-N-(4-pyridylmethyl)benzenesulfonamide | 4-ethoxy-N-(pyridin-4-ylmethyl)benzenesulfonamide | MLS000523416 | SMR000123394 | cid_676047
Type:
Small organic molecule
Emp. Form.:
C14H16N2O3S
Mol. Mass.:
292.353
SMILES:
CCOc1ccc(cc1)S(=O)(=O)NCc1ccncc1
Structure:
Search PDB for entries with ligand similarity: