Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM89255
Substrate
n/a
IC50
5539±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM89255
Synonyms:
4-[4-(4-methoxyphenyl)-1-piperazinyl]-5H-pyrimido[5,4-b]indole | 4-[4-(4-methoxyphenyl)piperazin-1-yl]-5H-pyrimido[5,4-b]indole | 4-[4-(4-methoxyphenyl)piperazino]-5H-pyrimid[5,4-b]indole | 4-[4-(4-methoxyphenyl)piperazino]-5H-pyrimido[5,4-b]indole | MLS000539554 | SMR000125212 | cid_1475855
Type:
Small organic molecule
Emp. Form.:
C21H21N5O
Mol. Mass.:
359.4243
SMILES:
COc1ccc(cc1)N1CCN(CC1)c1ncnc2c3ccccc3[nH]c12
Structure:
Search PDB for entries with ligand similarity: