Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM100224
Substrate
n/a
IC50
8200±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM100224
Synonyms:
1-[(4-methylsulfanylphenyl)methyl]-4-[(4-nitrophenyl)methyl]piperazine;oxalic acid | 1-[4-(methylthio)benzyl]-4-(4-nitrobenzyl)piperazine;oxalic acid | 1-[[4-(methylthio)phenyl]methyl]-4-[(4-nitrophenyl)methyl]piperazine;oxalic acid | MLS000687652 | SMR000283413 | cid_16195181 | ethanedioic acid;1-[(4-methylsulfanylphenyl)methyl]-4-[(4-nitrophenyl)methyl]piperazine
Type:
Small organic molecule
Emp. Form.:
C19H23N3O2S
Mol. Mass.:
357.47
SMILES:
CSc1ccc(CN2CCN(Cc3ccc(cc3)[N+]([O-])=O)CC2)cc1
Structure:
Search PDB for entries with ligand similarity: