Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM64718
Substrate
n/a
IC50
2212±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM64718
Synonyms:
MLS001000456 | N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-4-thieno[2,3-d]pyrimidinamine;hydrochloride | N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methyl-thieno[2,3-d]pyrimidin-4-amine;hydrochloride | N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine hydrochloride | N-[2-(3,4-dimethoxyphenyl)ethyl]-6-methylthieno[2,3-d]pyrimidin-4-amine;hydrochloride | SMR000498336 | cid_2974648 | homoveratryl-(6-methylthieno[2,3-d]pyrimidin-4-yl)amine;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C17H19N3O2S
Mol. Mass.:
329.417
SMILES:
COc1ccc(CCNc2ncnc3sc(C)cc23)cc1OC
Structure:
Search PDB for entries with ligand similarity: