Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM59548
Substrate
n/a
IC50
>85398±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM59548
Synonyms:
3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methyl-7-pyrazolo[1,5-a]pyrimidinamine | 3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-amine | 3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine | MLS001165929 | SMR000550192 | [3-(4-chlorophenyl)-6-(4-fluorophenyl)-5-methyl-pyrazolo[1,5-a]pyrimidin-7-yl]amine | cid_1474387
Type:
Small organic molecule
Emp. Form.:
C19H14ClFN4
Mol. Mass.:
352.793
SMILES:
Cc1nc2c(cnn2c(N)c1-c1ccc(F)cc1)-c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: