Reaction Details
Report a problem with these data
Report a problem with these dataTarget
COUP transcription factor 2
Ligand
BDBM93498
Substrate
n/a
IC50
359.98±n/a nM
Citation
PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Inhibitor
Name:
BDBM93498
Synonyms:
4-[2-(3,5-dimethyl-5-oxidanyl-2-oxidanylidene-cyclohexyl)-2-oxidanyl-ethyl]piperidine-2,6-dione | 4-[2-hydroxy-2-(5-hydroxy-2-keto-3,5-dimethyl-cyclohexyl)ethyl]piperidine-2,6-quinone | 4-[2-hydroxy-2-(5-hydroxy-3,5-dimethyl-2-oxocyclohexyl)ethyl]piperidine-2,6-dione | MLS002702844 | SMR001566667 | U-9361 | cid_91467
Type:
Small organic molecule
Emp. Form.:
C15H23NO5
Mol. Mass.:
297.3468
SMILES:
CC1CC(C)(O)CC(C(O)CC2CC(=O)NC(=O)C2)C1=O
Structure:
