Reaction Details
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Report a problem with these dataTarget
COUP transcription factor 2
Ligand
BDBM100257
Substrate
n/a
IC50
>4.27±n/a nM
Citation
PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] More Info.:
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
Inhibitor
Name:
BDBM100257
Synonyms:
MLS002703047 | SMR001566854 | Verrucarin A 9,10-epoxide | cid_181390
Type:
Small organic molecule
Emp. Form.:
C27H34O10
Mol. Mass.:
518.5529
SMILES:
[H]C12CC3OC(=O)C=CC=CC(=O)OCCC(C)C(O)C(=O)OCC4(CCC5(C)OC5C4O1)C3(C)C21CO1 |TLB:30:31:35:3.2,25:24:35:3.2,23:24:35:3.2,THB:37:35:32.24.31:3.2,36:35:32.24.31:3.2,4:3:35:32.24.31|
Structure:
