Reaction Details Report a problem with these data
Target
COUP transcription factor 2
Ligand
BDBM97192
Substrate
n/a
IC50
2009±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify inhibitors of COUP-TFII (NR2F2) PubChem Bioassay (2013)[AID] 
Target
Name:
COUP transcription factor 2
Synonyms:
ARP1 | COT2_HUMAN | COUP transcription factor 2 isoform a | NR2F2 | TFCOUP2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45583.83
Organism:
Homo sapiens (Human)
Description:
gi_14149746
Residue:
414
Sequence:
MAMVVSTWRDPQDEVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQGGPASTPAQTAAGGQGGPGGPGSDKQQQQQHIECVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQRGRMPPTQPTHGQFALTNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDMLLSGSSFNWPYMAIQ
  
Inhibitor
Name:
BDBM97192
Synonyms:
2-amino-N-(4-phenylbenzyl)quinoline-3-carboxamide | 2-amino-N-(biphenyl-4-ylmethyl)quinoline-3-carboxamide | 2-amino-N-[(4-phenylphenyl)methyl]-3-quinolinecarboxamide | 2-amino-N-[(4-phenylphenyl)methyl]quinoline-3-carboxamide | 2-azanyl-N-[(4-phenylphenyl)methyl]quinoline-3-carboxamide | MLS003678910 | SMR002356458 | cid_53382850
Type:
Small organic molecule
Emp. Form.:
C23H19N3O
Mol. Mass.:
353.4165
SMILES:
Nc1nc2ccccc2cc1C(=O)NCc1ccc(cc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: