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Target
Pro-glucagon
Ligand
BDBM100852
Substrate
n/a
Meas. Tech.
Glucagon SPA Assay
pH
7.4±0
Ki
28±0.0 nM
Citation
 Aspnes, GE; Didiuk, MT; Filipski, KJ; Guzman-Perez, A; Lee, EC; Pfefferkorn, JA; Stevens, BD; Tu, MM Glucagon receptor modulators US Patent  US8507533 Publication Date 8/13/2013 
Target
Name:
Pro-glucagon
Synonyms:
GCG | GLUC_HUMAN | Glucagon | Glucagon receptor (GCGR)
Type:
Enzyme
Mol. Mass.:
20907.95
Organism:
Homo sapiens (Human)
Description:
P01275
Residue:
180
Sequence:
MKSIYFVAGLFVMLVQGSWQRSLQDTEEKSRSFSASQADPLSDPDQMNEDKRHSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRDFPEEVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTKITDRK
  
Inhibitor
Name:
BDBM100852
Synonyms:
US8507533, 170 | US8507533, 419
Type:
Small organic molecule
Emp. Form.:
C27H30F3N5O3
Mol. Mass.:
529.554
SMILES:
Cc1cc(cc(C)c1-n1cc(cn1)C(F)(F)F)C(Nc1ccc(cn1)C(=O)NCCC(O)=O)C1CCCC1
Structure:
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