Target
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Ligand
BDBM101906
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
2.4e+2±n/a nM
Citation
 Fukuoka, MYokogawa, TMiyahara, SMiyakoshi, HYano, WTaguchi, JTakao, Y Uracil compound or salt thereof having human deoxyuridine triphosphatase inhibitory activity US Patent  US8530490 Publication Date 9/10/2013 
Target
Name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial
Synonyms:
DUT | DUT_HUMAN | Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) | Deoxyuridine triphosphatase (dUTPase) | dUTP pyrophosphatase
Type:
Enzyme
Mol. Mass.:
26574.03
Organism:
Homo sapiens (Human)
Description:
P33316
Residue:
252
Sequence:
MTPLCPRPALCYHFLTSLLRSAMQNARGARQRAEAAVLSGPGPPLGRAAQHGIPRPLSSAGRLSQGCRGASTVGAAGWKGELPKAGGSPAPGPETPAISPSKRARPAEVGGMQLRFARLSEHATAPTRGSARAAGYDLYSAYDYTIPPMEKAVVKTDIQIALPSGCYGRVAPRSGLAAKHFIDVGAGVIDEDYRGNVGVVLFNFGKEKFEVKKGDRIAQLICERIFYPEIEEVQALDDTERGSGGFGSTGKN
  
Inhibitor
Name:
BDBM101906
Synonyms:
CHEMBL2147975 | US8530490, 178
Type:
Small organic molecule
Emp. Form.:
C24H27N3O5S
Mol. Mass.:
469.553
SMILES:
CC(C)(NS(=O)(=O)c1cccc(OCC2CC2)c1)c1ccc(Cn2ccc(=O)[nH]c2=O)cc1
Structure:
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