Reaction Details Report a problem with these data
Target
Arachidonate 5-lipoxygenase-activating protein
Ligand
BDBM104626
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
3.0±0.0 nM
Citation
Bartolozzi, A; Bosanac, T; Chen, Z; De Lombaert, S; Dines, JA; Huber, JD; Liu, WW; Loke, PL; Morwick, TM; Olague, A; Riether, D; Tye, H; Wu, L; Zindell, RM Oxadiazole inhibitors of leukotriene production US Patent US8575201 Publication Date 11/5/2013
More Info.:
Target
Name:
Arachidonate 5-lipoxygenase-activating protein
Synonyms:
5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | 5-lipoxygenase/FLAP | AL5AP_HUMAN | ALOX5AP | FLAP | MK-886-binding protein
Type:
Enzyme
Mol. Mass.:
18159.90
Organism:
Homo sapiens (Human)
Description:
P20292
Residue:
161
Sequence:
MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP