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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM114601
Substrate
n/a
Meas. Tech.
Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
76083±n/a nM
Citation
 PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay (2013)[AID] 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:
Enzyme
Mol. Mass.:
52843.00
Organism:
Mus musculus (Mouse)
Description:
P35363
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM114601
Synonyms:
1-(6-bromanylnaphthalen-2-yl)oxy-3-(4-pyridin-2-ylpiperazin-1-yl)propan-2-ol | 1-(6-bromo-2-naphthoxy)-3-[4-(2-pyridyl)piperazino]propan-2-ol | 1-(6-bromonaphthalen-2-yl)oxy-3-(4-pyridin-2-ylpiperazin-1-yl)propan-2-ol | 1-[(6-bromo-2-naphthalenyl)oxy]-3-[4-(2-pyridinyl)-1-piperazinyl]-2-propanol | SR-01000628121 | SR-01000628121-2 | cid_2950243
Type:
Small organic molecule
Emp. Form.:
C22H24BrN3O2
Mol. Mass.:
442.349
SMILES:
OC(COc1ccc2cc(Br)ccc2c1)CN1CCN(CC1)c1ccccn1
Structure:
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