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Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM114603
Substrate
n/a
Meas. Tech.
Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A)
EC50
76083±n/a nM
Citation
 PubChem, PC Late stage for the probe development effort to identify agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A): Luminescence-based cell-based high throughput dose response assay for agonists of the mouse 5-hydroxytryptamine (serotonin) receptor 2A (HTR2A) PubChem Bioassay (2013)[AID] 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2 | 5-HT-2A | 5-hydroxytryptamine receptor 2A | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_MOUSE | Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor | Htr2 | Htr2a | Serotonin 2a (5-HT2a) receptor
Type:
Enzyme
Mol. Mass.:
52843.00
Organism:
Mus musculus (Mouse)
Description:
P35363
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDDSRLYPNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLSSFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPTLAYKSSQLQVGQKKNSQEDAEPTANDCSMVTLGNQHSEEMCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM114603
Synonyms:
N-[[3-(2-fluorophenyl)-1-methyl-4-pyrazolyl]methyl]-1-[1-(3-methoxyphenyl)-4-pyrazolyl]methanamine | N-[[3-(2-fluorophenyl)-1-methyl-pyrazol-4-yl]methyl]-1-[1-(3-methoxyphenyl)pyrazol-4-yl]methanamine | N-[[3-(2-fluorophenyl)-1-methylpyrazol-4-yl]methyl]-1-[1-(3-methoxyphenyl)pyrazol-4-yl]methanamine | SR-01000757080 | SR-01000757080-2 | [3-(2-fluorophenyl)-1-methyl-pyrazol-4-yl]methyl-[[1-(3-methoxyphenyl)pyrazol-4-yl]methyl]amine | cid_16189988
Type:
Small organic molecule
Emp. Form.:
C22H22FN5O
Mol. Mass.:
391.4414
SMILES:
COc1cccc(c1)-n1cc(CNCc2cn(C)nc2-c2ccccc2F)cn1
Structure:
Search PDB for entries with ligand similarity: