Target
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2
Ligand
BDBM50428795
Substrate
n/a
IC50
3.9e+3±n/a nM
Citation
 Hrast, MSosic, ISink, RGobec, S Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F. Bioorg Chem 55:2-15 (2014) [PubMed]  Article 
Target
Name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2
Synonyms:
MURA2_STAAM | MurA (S. aureus) | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | murA2 | murZ
Type:
Protein
Mol. Mass.:
45068.88
Organism:
Staphylococcus aureus (Firmicutes)
Description:
S. aureus MurA
Residue:
419
Sequence:
MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLEGLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGAMLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIFLDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKINGVKELHGSEYQVIPDRIEAGTYMCIAAACGENVILNNIVPKHVETLTAKFSELGVNVDVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYPERFKHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYNVKHIYRGYTDIVEHLKALGADIWTETV
  
Inhibitor
Name:
BDBM50428795
Synonyms:
CHEMBL2335230 | MurA inhibitor (compound 7)
Type:
Small organic molecule
Emp. Form.:
C6H3Br2NO3
Mol. Mass.:
296.901
SMILES:
[O-][N+](=O)C(\Br)=C\c1ccc(Br)o1
Structure:
Search PDB for entries with ligand similarity: