Reaction Details Report a problem with these data
Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM119483
Substrate
n/a
Meas. Tech.
Cell Response Assay
IC50
51±n/a nM
Citation
 Tatani, K; Kawamura, N; Kondo, T; Kondo, A Indole derivative or pharmaceutically acceptable salt thereof US Patent  US8680120 Publication Date 3/25/2014 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_RAT | Prostanoid EP1 receptor | Ptger1
Type:
Enzyme
Mol. Mass.:
43080.10
Organism:
Rattus norvegicus (Rat)
Description:
P70597
Residue:
405
Sequence:
MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
  
Inhibitor
Name:
BDBM119483
Synonyms:
US8680120, 25-44
Type:
Small organic molecule
Emp. Form.:
C20H21ClN2O3
Mol. Mass.:
372.845
SMILES:
CCC(C)c1cc2cc(OC)c(Cl)cc2n1Cc1cccc(n1)C(O)=O
Structure:
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