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Target
DNA primase
Ligand
BDBM4078
Substrate
n/a
Meas. Tech.
Quatitative Inhibition Analysis Assay
pH
8.8±n/a
IC50
>1.00e+5±n/a nM
Comments
extracted
Citation
 Biswas, T; Green, KD; Garneau-Tsodikova, S; Tsodikov, OV Discovery of inhibitors of Bacillus anthracis primase DnaG. Biochemistry 52:6905-10 (2013) [PubMed]  Article 
Target
Name:
DNA primase
Synonyms:
DNA primase (Ba DnaG)
Type:
Protein
Mol. Mass.:
68258.37
Organism:
Bacillus anthracis (Firmicutes)
Description:
A0A6L8PXB3
Residue:
598
Sequence:
MGNRIPEEVVEQIRTSSDIVEVIGEYVQLRKQGRNYFGLCPFHGENSPSFSVSSDKQIFHCFGCGEGGNVFSFLMKMEGLAFTEAVQKLGERNGIAVAEYTSGQGQQEDISDDTVIMQQAHELLKKYYHHLLVNTEEGNEALSYLLKRGITKEMIEKFEIGYASPAWDAATKILQKRGLSLSSMEQAGLLIRSEKDGSHYDRFRGRVMFPIYTLQGKVIAFSGRALGDDTPKYLNSPETPIFHKSKLLYNFHQARPFIRKRGQVVLFEGYADVLAAVKSGVEEAVATMGTALTEEQAKLLRRNVETVVLCYDGDKAGREATMKAGQLLLQVGCQVKVTSLPDKLDPDEYVQQYGTTAFENLVKSSISFVGFKINYLRLGKNLQDESGKEEYVKSVLKELSLLQDAMQAESYLKSLSQEFSYSMETLLNQLHQYRKEQKVQQKQVKQVSKPSQIVQTKPKLTGFERAEREIIYHMLQSPEVAVRMESHIEDFHTEEHKGILYELYAYYEKGNEPSVGTFLSWLSDEKLKNIITDISTDEFINPEYTEEVLQSHLETLRRHQEKLEKMEIIFKIKQMEKTDPVEAAKYYVAYLQNQKARK
  
Inhibitor
Name:
BDBM4078
Synonyms:
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione | CHEMBL6246 | ELLAGIC ACID | Elagic Acid | Ellagic acid (18) | Ellagic acid dihydrate | MLS000069632 | SMR000058244 | cid_5281855
Type:
Small organic molecule
Emp. Form.:
C14H6O8
Mol. Mass.:
302.1926
SMILES:
Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O
Structure:
Search PDB for entries with ligand similarity: