Reaction Details Report a problem with these data
Target
Galectin-1
Ligand
BDBM120776
Substrate
n/a
Meas. Tech.
Fluorescence Polarization-Based Assay
Kd
6300±n/a nM
Citation
 Leffler, H; Nilsson, UJ; Von Wachenfeldt, H Galactoside inhibitors of galectins US Patent  US8703720 Publication Date 4/22/2014 
Target
Name:
Galectin-1
Synonyms:
14 kDa lectin | Galaptin | HPL | LEG1_HUMAN | LGALS1 | Lactose-binding lectin 1 | Lectin galactoside-binding soluble 1 | Putative MAPK-activating protein PM12
Type:
beta galactoside-binding protein
Mol. Mass.:
14713.53
Organism:
Homo sapiens (Human)
Description:
P09382
Residue:
135
Sequence:
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD
  
Inhibitor
Name:
BDBM120776
Synonyms:
US8703720, 23
Type:
Small organic molecule
Emp. Form.:
C26H30Cl2N2O7S
Mol. Mass.:
585.497
SMILES:
OCC1O[C@@H](S[C@@H]2CCCC(NC(=O)c3ccc(Cl)cc3)C2O)C(O)[C@@H](NC(=O)c2ccc(Cl)cc2)[C@H]1O |r|
Structure:
Search PDB for entries with ligand similarity: