Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM121482
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
1.88±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzodioxole piperazine compounds US Patent  US8722683 Publication Date 5/13/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM121482
Synonyms:
US8722683, 29
Type:
Small organic molecule
Emp. Form.:
C23H33N3O4
Mol. Mass.:
415.5258
SMILES:
OC1(CC1)C(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 |r,wU:7.7,wD:10.11,(9.27,-.82,;8.5,.52,;9.98,.92,;8.89,2.01,;6.96,.52,;6.19,-.82,;6.19,1.85,;4.65,1.85,;3.88,.52,;2.34,.52,;1.57,1.85,;.03,1.85,;-.74,.52,;-2.28,.52,;-3.05,-.82,;-4.59,-.82,;-5.36,.52,;-4.59,1.85,;-3.05,1.85,;-6.9,.52,;-7.67,1.85,;-9.21,1.85,;-9.98,.52,;-9.21,-.82,;-9.69,-2.28,;-8.44,-3.19,;-7.2,-2.28,;-7.67,-.82,;2.34,3.19,;3.88,3.19,)|
Structure:
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