Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM121504
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
2.11±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzodioxole piperazine compounds US Patent  US8722683 Publication Date 5/13/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM121504
Synonyms:
US8722683, 51
Type:
Small organic molecule
Emp. Form.:
C28H35N3O5
Mol. Mass.:
493.5946
SMILES:
O=C(Cc1ccc2OCOc2c1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 |r,wU:13.14,wD:16.18,(4.56,-2.05,;5.33,-.72,;6.87,-.72,;7.64,.61,;6.87,1.95,;7.64,3.28,;9.18,3.28,;10.21,4.42,;11.61,3.8,;11.45,2.27,;9.95,1.95,;9.18,.61,;4.56,.61,;3.02,.61,;2.25,-.72,;.71,-.72,;-.06,.61,;-1.6,.61,;-2.37,-.72,;-3.91,-.72,;-4.68,-2.05,;-6.22,-2.05,;-6.99,-.72,;-6.22,.61,;-4.68,.61,;-8.53,-.72,;-9.3,.61,;-10.84,.61,;-11.61,-.72,;-10.84,-2.05,;-11.32,-3.52,;-10.07,-4.42,;-8.83,-3.52,;-9.3,-2.05,;.71,1.95,;2.25,1.95,)|
Structure:
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