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Target
D(3) dopamine receptor
Ligand
BDBM121506
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
2.09±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzodioxole piperazine compounds US Patent  US8722683 Publication Date 5/13/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM121506
Synonyms:
US8722683, 53
Type:
Small organic molecule
Emp. Form.:
C26H39N3O4
Mol. Mass.:
457.6056
SMILES:
O=C(CC1CCOCC1)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 |r,wU:10.10,wD:13.14,(5.39,-1.48,;6.16,-.15,;7.7,-.15,;8.47,1.18,;10.01,1.18,;10.78,2.52,;10.01,3.85,;8.47,3.85,;7.7,2.52,;5.39,1.18,;3.85,1.18,;3.08,-.15,;1.54,-.15,;.77,1.18,;-.77,1.18,;-1.54,-.15,;-3.08,-.15,;-3.85,-1.48,;-5.39,-1.48,;-6.16,-.15,;-5.39,1.18,;-3.85,1.18,;-7.7,-.15,;-8.47,1.18,;-10.01,1.18,;-10.78,-.15,;-10.01,-1.48,;-10.49,-2.95,;-9.24,-3.85,;-7.99,-2.95,;-8.47,-1.48,;1.54,2.52,;3.08,2.52,)|
Structure:
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