Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM121509
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
3.37±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzodioxole piperazine compounds US Patent  US8722683 Publication Date 5/13/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM121509
Synonyms:
US8722683, 56
Type:
Small organic molecule
Emp. Form.:
C28H43N3O4
Mol. Mass.:
485.6587
SMILES:
CO[C@H]1CC[C@H](CC(=O)N[C@H]2CC[C@H](CCN3CCN(CC3)c3cccc4OCOc34)CC2)CC1 |r,wU:10.9,2.1,wD:13.13,5.5,(11.55,4.52,;10.01,4.52,;9.24,3.19,;10.01,1.85,;9.24,.52,;7.7,.52,;6.93,-.82,;5.39,-.82,;4.62,-2.15,;4.62,.52,;3.08,.52,;2.31,-.82,;.77,-.82,;,.52,;-1.54,.52,;-2.31,-.82,;-3.85,-.82,;-4.62,-2.15,;-6.16,-2.15,;-6.93,-.82,;-6.16,.52,;-4.62,.52,;-8.47,-.82,;-9.24,.52,;-10.78,.52,;-11.55,-.82,;-10.78,-2.15,;-11.26,-3.61,;-10.01,-4.52,;-8.76,-3.61,;-9.24,-2.15,;.77,1.85,;2.31,1.85,;6.93,1.85,;7.7,3.19,)|
Structure:
Search PDB for entries with ligand similarity: