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Target
D(3) dopamine receptor
Ligand
BDBM121529
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
3.36±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzodioxole piperazine compounds US Patent  US8722683 Publication Date 5/13/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM121529
Synonyms:
US8722683, 76
Type:
Small organic molecule
Emp. Form.:
C21H34N4O4S
Mol. Mass.:
438.584
SMILES:
CN(C)S(=O)(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2cccc3OCOc23)CC1 |r,wU:7.6,wD:10.10,(9.76,-.17,;8.27,-.57,;7.87,-2.06,;7.18,.52,;5.85,-.25,;8.52,1.29,;6.41,1.85,;4.87,1.85,;4.1,.52,;2.56,.52,;1.79,1.85,;.25,1.85,;-.52,.52,;-2.06,.52,;-2.83,-.82,;-4.37,-.82,;-5.14,.52,;-4.37,1.85,;-2.83,1.85,;-6.68,.52,;-7.45,1.85,;-8.99,1.85,;-9.76,.52,;-8.99,-.82,;-9.46,-2.28,;-8.22,-3.19,;-6.97,-2.28,;-7.45,-.82,;2.56,3.19,;4.1,3.19,)|
Structure:
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