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Target
Cathepsin S
Ligand
BDBM123098
Substrate
n/a
Meas. Tech.
Enzyme Assay
Ki
21000±n/a nM
Citation
 Odén, LS; Nilsson, M; Kahnberg, P; Samuelsson, B; Grabowska, U Protease inhibitors US Patent  US8735395 Publication Date 5/27/2014 
Target
Name:
Cathepsin S
Synonyms:
CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein
Type:
Protein
Mol. Mass.:
37507.38
Organism:
Homo sapiens (Human)
Description:
P25774
Residue:
331
Sequence:
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
  
Inhibitor
Name:
BDBM123098
Synonyms:
US10723709, Example 2 | US11312693, Example 2 | US8735395, 2 | US9200006, 2
Type:
Small organic molecule
Emp. Form.:
C29H34FN5O4S
Mol. Mass.:
567.675
SMILES:
CC(C)C[C@H](NC(=O)c1ccc(cc1)-c1nc(sc1F)N1CCN(C)CC1)C(=O)N1C[C@@H](C#C)[C@H]2OCC(=O)[C@@H]12 |r|
Structure:
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