Reaction Details Report a problem with these data
Target
Interleukin-2
Ligand
BDBM128386
Substrate
n/a
Meas. Tech.
Inhibition Assay
IC50
6.4±n/a nM
Citation
 Sun, L; Chen, S; Jiang, J; Xia, Z; Xie, Y; Yu, C Thiophene compounds for inflammation and immune-related uses US Patent  US8802721 Publication Date 8/12/2014 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM128386
Synonyms:
US8802721, 3
Type:
Small organic molecule
Emp. Form.:
C20H15F2NO3S
Mol. Mass.:
387.4
SMILES:
COC(=O)c1ccc(C)c(c1)-c1ccc(s1)C(=O)Nc1c(F)cccc1F
Structure:
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