Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM136363
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±n/a
Ki
0.16±n/a nM
Comments
extracted
Citation
 Andersson, J; Gyback, H; Johansson, A; Linde, CE; Malmstrom, J; Nordvall, G; Weigelt, T; Terp, G 2-carboxamide-7-piperazinyl-benzofuran derivatives US Patent  US8859534 Publication Date 10/14/2014 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-hydroxytryptamine receptor 1A (5HT1A)
Type:
Protein
Mol. Mass.:
46351.20
Organism:
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Description:
G3I1B6
Residue:
422
Sequence:
MDIFSLGQGNNTTSSQEPFGTGGNVTGISDVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSDPDACTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGASTSLSTSSAPPPKKSLNGQPGNGDWRRSAENRAVGAPCANGAVRQGDDEATLEVIEVHRVGNSKDHLPLPSESGATSYAPACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR
  
Inhibitor
Name:
BDBM136363
Synonyms:
US8859534, 49
Type:
Small organic molecule
Emp. Form.:
C28H32N4O3
Mol. Mass.:
472.5787
SMILES:
CC(=O)N1CCc2cc(CCN3CCN(CC3)c3cccc4cc(oc34)C(=O)N3CCC3)ccc12
Structure:
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