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Target
Transthyretin
Ligand
BDBM138358
Substrate
n/a
Meas. Tech.
FP Assay
IC50
296±n/a nM
Citation
 Graef, IA; Alhamadsheh, M Identification of stabilizers of multimeric proteins US Patent  US8877795 Publication Date 11/4/2014 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM138358
Synonyms:
US10278929, Compound 7 | US11337935, Compound 7 | US8877795, 7
Type:
Small organic molecule
Emp. Form.:
C14H17FN2O
Mol. Mass.:
248.296
SMILES:
Cc1n[nH]c(C)c1CCCOc1ccccc1F
Structure:
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