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Target
D(3) dopamine receptor
Ligand
BDBM141768
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
0.68±n/a nM
Citation
 Rodriguez Sarmiento, RM; Wichmann, J Benzofurane-piperidine compounds US Patent  US8921397 Publication Date 12/30/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM141768
Synonyms:
US8921397, 10
Type:
Small organic molecule
Emp. Form.:
C27H35N3O3
Mol. Mass.:
449.5851
SMILES:
Cc1cc(CC(=O)N[C@H]2CC[C@H](CCN3CCC(CC3)c3coc4ccccc34)CC2)on1 |r,wU:11.11,wD:8.7,(11.52,-2.23,;10.18,-1.46,;9.71,,;8.17,,;7.4,1.33,;5.86,1.33,;5.09,2.67,;5.09,,;3.55,,;2.78,1.33,;1.24,1.33,;.47,,;-1.07,,;-1.84,-1.33,;-3.38,-1.33,;-4.15,-2.67,;-5.69,-2.67,;-6.46,-1.33,;-5.69,,;-4.15,,;-8,-1.33,;-8.91,-2.58,;-10.37,-2.1,;-10.37,-.56,;-11.52,.47,;-11.2,1.97,;-9.73,2.45,;-8.59,1.42,;-8.91,-.09,;1.24,-1.33,;2.78,-1.33,;7.69,-1.46,;8.94,-2.37,)|
Structure:
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