Reaction Details Report a problem with these data
Target
NAD kinase
Ligand
BDBM141969
Substrate
n/a
Meas. Tech.
Inhibitor Assay
Ki
50000±n/a nM
Citation
 Pochet, S; Labesse, G; Gelin, M; Assairi, L; Dussurget, O; Poncet-Montange, G Antibacterial compounds US Patent  US8927520 Publication Date 1/6/2015 
Target
Name:
NAD kinase
Synonyms:
NAD kinase (NADK) | NADK_STAAC | nadK
Type:
Protein
Mol. Mass.:
30776.91
Organism:
Staphylococcus aureus
Description:
Q5HH78
Residue:
269
Sequence:
MRYTILTKGDSKSNALKHKMMNYMKDFRMIEDSENPEIVISVGGDGTLLQAFHQYSHMLSKVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPLLEIIMRYNDNGYETRYLALNEATMKTENGSTLVVDVNLRGKHFERFRGDGLCVSTPSGSTAYNKALGGALIHPSLEAMQITEIASINNRVFRTVGSPLVLPKHHTCLISPVNHDTIRMTIDHVSIKHKNVNSIQYRVANEKVRFARFRPFPFWKRVHDSFISSDEER
  
Inhibitor
Name:
BDBM141969
Synonyms:
US8927520, 17
Type:
Small organic molecule
Emp. Form.:
C22H28N12O7S
Mol. Mass.:
604.599
SMILES:
NC[C@H]1O[C@H]([C@@H](O)C1O)n1c(SCC(=O)NC[C@H]2O[C@H]([C@@H](O)C2O)n2cnc3c(N)ncnc23)nc2c(N)ncnc12 |r|
Structure:
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