Target
5-hydroxytryptamine receptor 2A
Ligand
BDBM152814
Substrate
n/a
Meas. Tech.
Receptor Binding Assay
pH
7.5±n/a
IC50
0.51±n/a nM
Comments
extracted
Citation
 Zhang, GChen, YXu, XLiu, BFeng, XZhao, SLiu, SYu, MLan, YQiu, Y [1,3,4] oxadiazole derivative and application thereof US Patent  US8993575 Publication Date 3/31/2015 
Target
Name:
5-hydroxytryptamine receptor 2A
Synonyms:
5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52852.05
Organism:
Rattus norvegicus (rat)
Description:
Rat cortex membranes 5-HT2A receptors.
Residue:
471
Sequence:
MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGYLPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSFVAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYKSSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
  
Inhibitor
Name:
BDBM152814
Synonyms:
US8993575, 4
Type:
Small organic molecule
Emp. Form.:
C24H25FN4O3S
Mol. Mass.:
468.544
SMILES:
OCc1ccc(cc1)-c1nnc(SCCCN2CCC(CC2)c2noc3cc(F)ccc23)o1
Structure:
Search PDB for entries with ligand similarity: