Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, intestinal
Ligand
BDBM50085042
Substrate
n/a
Meas. Tech.
Fluorophore Displacement Assay
Temperature
566.3±0 K
Ki
6.1e+3± 6e+1 nM
Citation
 Patil, R; Laguerre, A; Wielens, J; Headey, SJ; Williams, ML; Hughes, ML; Mohanty, B; Porter, CJ; Scanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol 9:2526-34 (2014) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, intestinal
Synonyms:
FABP2 | FABPI | FABPI_HUMAN | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP | Intestinal fatty acid-binding protein (hIFABP)
Type:
Protein
Mol. Mass.:
15207.56
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
132
Sequence:
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
  
Inhibitor
Name:
BDBM50085042
Synonyms:
2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester | CHEMBL672 | FENOFIBRATE | FNF | Fenofibric acid | Finofibrate | Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate | Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate | Lipantil (TN) | Procetofen | Tricor (TN) | propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
Type:
Small organic molecule
Emp. Form.:
C20H21ClO4
Mol. Mass.:
360.831
SMILES:
CC(C)OC(=O)C(C)(C)Oc1ccc(cc1)C(=O)c1ccc(Cl)cc1
Structure:
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