Reaction Details Report a problem with these data
Target
Fatty acid-binding protein, intestinal
Ligand
BDBM50022271
Substrate
n/a
Meas. Tech.
Fluorophore Displacement Assay
Temperature
566.3±0 K
Ki
8.24e+4± 3e+1 nM
Citation
 Patil, R; Laguerre, A; Wielens, J; Headey, SJ; Williams, ML; Hughes, ML; Mohanty, B; Porter, CJ; Scanlon, MJ Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein. ACS Chem Biol 9:2526-34 (2014) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein, intestinal
Synonyms:
FABP2 | FABPI | FABPI_HUMAN | Fatty acid binding protein intestinal | Fatty acid-binding protein, intestinal | I-FABP | Intestinal fatty acid-binding protein (hIFABP)
Type:
Protein
Mol. Mass.:
15207.56
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
132
Sequence:
MAFDSTWKVDRSENYDKFMEKMGVNIVKRKLAAHDNLKLTITQEGNKFTVKESSAFRNIEVVFELGVTFNYNLADGTELRGTWSLEGNKLIGKFKRTDNGNELNTVREIIGDELVQTYVYEGVEAKRIFKKD
  
Inhibitor
Name:
BDBM50022271
Synonyms:
2-(3-Benzoylphenyl)propionic acid | 2-(3-benzoylphenyl)propanoic acid | 3-Benzoyl-alpha-methylbenzeneacetic acid | 3-Benzoylhydratropic acid | CHEMBL571 | Dexketoprofen trometamol | KETOPROFEN | L'Acide (benzoyl-3-phenyl)-2-propionique | Orudis (TN) | m-Benzoylhydratropic acid
Type:
Small organic molecule
Emp. Form.:
C16H14O3
Mol. Mass.:
254.2806
SMILES:
CC(C(O)=O)c1cccc(c1)C(=O)c1ccccc1
Structure:
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