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Target
PHD finger protein 19
Ligand
BDBM154548
Substrate
n/a
Meas. Tech.
AlphaScreen Assay
pH
8±0
Temperature
1937.05±0 K
IC50
>5.00e+5±n/a nM
Citation
 Perfetti, MT; Baughman, BM; Dickson, BM; Mu, Y; Cui, G; Mader, P; Dong, A; Norris, JL; Rothbart, SB; Strahl, BD; Brown, PJ; Janzen, WP; Arrowsmith, CH; Mer, G; McBride, KM; James, LI; Frye, SV Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. ACS Chem Biol 10:1072-81 (2015) [PubMed]  Article 
Target
Name:
PHD finger protein 19
Synonyms:
PCL3 | PHD finger protein 19 (PHF19) | PHF19 | PHF19_HUMAN
Type:
Protein
Mol. Mass.:
65617.90
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
580
Sequence:
MENRALDPGTRDSYGATSHLPNKGALAKVKNNFKDLMSKLTEGQYVLCRWTDGLYYLGKIKRVSSSKQSCLVTFEDNSKYWVLWKDIQHAGVPGEEPKCNICLGKTSGPLNEILICGKCGLGYHQQCHIPIAGSADQPLLTPWFCRRCIFALAVRKGGALKKGAIARTLQAVKMVLSYQPEELEWDSPHRTNQQQCYCYCGGPGEWYLRMLQCYRCRQWFHEACTQCLNEPMMFGDRFYLFFCSVCNQGPEYIERLPLRWVDVVHLALYNLGVQSKKKYFDFEEILAFVNHHWELLQLGKLTSTPVTDRGPHLLNALNSYKSRFLCGKEIKKKKCIFRLRIRVPPNPPGKLLPDKGLLPNENSASSELRKRGKSKPGLLPHEFQQQKRRVYRRKRSKFLLEDAIPSSDFTSAWSTNHHLASIFDFTLDEIQSLKSASSGQTFFSDVDSTDAASTSGSASTSLSYDSRWTVGSRKRKLAAKAYMPLRAKRWAAELDGRCPSDSSAEGASVPERPDEGIDSHTFESISEDDSSLSHLKSSITNYFGAAGRLACGEKYQVLARRVTPEGKVQYLVEWEGTTPY
  
Inhibitor
Name:
BDBM154548
Synonyms:
3-Bromo-N-(3-(tert-butyl(methyl)amino)propyl)benzamide (UNC2892, 4)
Type:
Small organic molecule
Emp. Form.:
C15H23BrN2O
Mol. Mass.:
327.26
SMILES:
CN(CCCNC(=O)c1cccc(Br)c1)C(C)(C)C
Structure:
Search PDB for entries with ligand similarity: