Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50448210
Substrate
n/a
Meas. Tech.
Receptor Assay
pH
7.4±n/a
IC50
8.6±n/a nM
Comments
extracted
Citation
 Zhang, G; Chen, Y; Xu, X; Liu, X; Zhao, S; Liu, B; Yu, M; Qiu, Y Alicyclic[c] benzopyrone derivatives and uses thereof US Patent  US9018213 Publication Date 4/28/2015 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3
Type:
Protein
Mol. Mass.:
49540.58
Organism:
Rattus norvegicus (Rat)
Description:
P19020
Residue:
446
Sequence:
MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSICSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQQSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLKRYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGPLQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYVNSALNPVIYTTFNVEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50448210
Synonyms:
CHEMBL3120697 | US9018213, 15
Type:
Small organic molecule
Emp. Form.:
C28H28ClFN2O4
Mol. Mass.:
510.984
SMILES:
Fc1ccc2c(noc2c1)C1CCN(CCCCOc2ccc3c4CCCc4c(=O)oc3c2Cl)CC1
Structure:
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