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Target
5-hydroxytryptamine receptor 2C
Ligand
BDBM155943
Substrate
n/a
Meas. Tech.
Receptor Binding Assay
IC50
1489.2±n/a nM
Citation
 Zhang, G; Chen, Y; Xu, X; Liu, X; Zhao, S; Liu, B; Yu, M; Qiu, Y Alicyclic[c] benzopyrone derivatives and uses thereof US Patent  US9018213 Publication Date 4/28/2015 
Target
Name:
5-hydroxytryptamine receptor 2C
Synonyms:
5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
Type:
Enzyme
Mol. Mass.:
51935.10
Organism:
Rattus norvegicus (Rat)
Description:
P08909
Residue:
460
Sequence:
MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
  
Inhibitor
Name:
BDBM155943
Synonyms:
US9018213, 14
Type:
Small organic molecule
Emp. Form.:
C27H28ClN3O3S
Mol. Mass.:
510.048
SMILES:
Clc1c(OCCCCN2CCN(CC2)c2nsc3ccccc23)ccc2c3CCCc3c(=O)oc12
Structure:
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