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Target
Methyl-CpG-binding protein 2
Ligand
BDBM158508
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
16900±n/a nM
Citation
 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z Agents for reversing epigenetic silencing of genes US Patent  US9034574 Publication Date 5/19/2015 
Target
Name:
Methyl-CpG-binding protein 2
Synonyms:
MECP2 | MECP2_HUMAN | Small conductance calcium-activated potassium channel protein 3
Type:
n/a
Mol. Mass.:
52482.84
Organism:
Homo sapiens (Human)
Description:
P51608
Residue:
486
Sequence:
MVAGMLGLREEKSEDQDLQGLKDKPLKFKKVKKDKKEEKEGKHEPVQPSAHHSAEPAEAGKAETSEGSGSAPAVPEASASPKQRRSIIRDRGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIAYFEKVGDTSLDPNDFDFTVTGRGSPSRREQKPPKKPKSPKAPGTGRGRGRPKGSGTTRPKAATSEGVQVKRVLEKSPGKLLVKMPFQTSPGGKAEGGGATTSTQVMVIKRPGRKRKAEADPQAIPKKRGRKPGSVVAAAAAEAKKKAVKESSIRSVQETVLPIKKRKTRETVSIEVKEVVKPLLVSTLGEKSGKGLKTCKSPGRKSKESSPKGRSSSASSPPKKEHHHHHHHSESPKAPVPLLPPLPPPPPEPESSEDPTSPPEPQDLSSSVCKEEKMPRGGSLESDGCPKEPAKTQPAVATAATAAEKYKHRGEGERKDIVSSSMPRPNREEPVDSRTPVTERVS
  
Inhibitor
Name:
BDBM158508
Synonyms:
US9034574, XVII
Type:
Small organic molecule
Emp. Form.:
C14H12N2OS
Mol. Mass.:
256.323
SMILES:
Oc1ccc(cc1)C1NN=C(S1)c1ccccc1 |c:10|
Structure:
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