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Target
Methyl-CpG-binding domain protein 2
Ligand
BDBM158507
Substrate
n/a
Meas. Tech.
Binding Assay
IC50
6140±n/a nM
Citation
 Nelson, WG; Yegnasubramanian, S; Lin, X; Speed, TJ; Reichert, Z Agents for reversing epigenetic silencing of genes US Patent  US9034574 Publication Date 5/19/2015 
Target
Name:
Methyl-CpG-binding domain protein 2
Synonyms:
MBD2 | MBD2_HUMAN | Methyl-CpG binding domain protein 2 | Methyl-CpG-binding domain protein 2 (MBD2)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43278.74
Organism:
Homo sapiens (Human)
Description:
gi_21595776
Residue:
411
Sequence:
MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGGAPRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYFSPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLNTTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQIIKTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCKAFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA
  
Inhibitor
Name:
BDBM158507
Synonyms:
US9034574, Add | US9034574, III
Type:
Small organic molecule
Emp. Form.:
C16H12N4O2
Mol. Mass.:
292.2921
SMILES:
Cn1c2ccccc2n2cc(nc12)-c1ccc(cc1)[N+]([O-])=O
Structure:
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