Reaction Details
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Beta-lactamase SHV-1
Ligand
BDBM178165
Substrate
n/a
Meas. Tech.
Cell Free Inhibition Assay
pH
7±n/a
Temperature
310.15±n/a K
IC50
4.3±n/a nM
Comments
extracted
Citation
More Info.:
Target
Name:
Beta-lactamase SHV-1
Synonyms:
BLA1_ECOLX | Beta-lactamase (SHV-1) | bla | shv1
Type:
Enzyme
Mol. Mass.:
31226.68
Organism:
Escherichia coli
Description:
P0AD63
Residue:
286
Sequence:
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
Inhibitor
Name:
BDBM178165
Synonyms:
US9120808, Mixture of Example 43 and Example 44
Type:
Small organic molecule
Emp. Form.:
C12H12INO6
Mol. Mass.:
393.1313
SMILES:
COC(=O)C1N2[C@@H](CC2=O)O\C1=C1/CC(CI)OC1=O |r|
Structure:
