Target
D(3) dopamine receptor
Ligand
BDBM180699
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
Ki
4.749±n/a nM
Citation
 Gobbi, LJaeschke, GRoche, OSarmiento, RMSteward, L Dual modulators of 5HT2A and D3 receptors US Patent  US8829029 Publication Date 9/9/2014 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM180699
Synonyms:
US8829029, 3
Type:
Small organic molecule
Emp. Form.:
C24H34FN3O3
Mol. Mass.:
431.5435
SMILES:
COCCC(=O)N[C@H]1CC[C@H](CCN2CCC(CC2)c2noc3cc(F)ccc23)CC1 |r,wU:7.6,wD:10.10,(9.34,.38,;8,1.15,;8,2.69,;6.67,3.46,;6.67,5,;8,5.77,;5.33,5.77,;4,5,;4,3.46,;2.67,2.69,;1.33,3.46,;,2.69,;-1.33,3.46,;-2.67,2.69,;-2.67,1.15,;-4,.38,;-5.33,1.15,;-5.33,2.69,;-4,3.46,;-6.67,.38,;-8,1.15,;-9.34,-1.16,;-8,-1.93,;-8,-3.47,;-6.67,-4.24,;-6.67,-5.78,;-5.33,-3.47,;-5.33,-1.93,;-6.67,-1.16,;1.33,5,;2.67,5.78,)|
Structure:
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