Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50011300
Substrate
n/a
Meas. Tech.
Competition Binding Assay
pH
7.4±n/a
Ki
8±n/a nM
Comments
extracted
Citation
 Cabri, W; Minetti, P; Piersanti, G; Tarzia, G Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments US Patent  US9133197 Publication Date 9/15/2015 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50011300
Synonyms:
CHEMBL2398482 | US9133197, 2
Type:
Small organic molecule
Emp. Form.:
C12H16N8O
Mol. Mass.:
288.3084
SMILES:
CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1
Structure:
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