Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50011300
Substrate
n/a
Meas. Tech.
Competition Binding Assay
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
27±n/a nM
Comments
extracted
Citation
 Cabri, W; Minetti, P; Piersanti, G; Tarzia, G Oxidated derivatives of triazolylpurines useful as ligands of the adenosine A2A receptor and their use as medicaments US Patent  US9133197 Publication Date 9/15/2015 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50011300
Synonyms:
CHEMBL2398482 | US9133197, 2
Type:
Small organic molecule
Emp. Form.:
C12H16N8O
Mol. Mass.:
288.3084
SMILES:
CC(O)CCc1nc(N)c2nc(-n3nccn3)n(C)c2n1
Structure:
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