Reaction Details Report a problem with these data
Target
Peroxisome proliferator-activated receptor alpha [169-468]
Ligand
BDBM190488
Substrate
n/a
Meas. Tech.
Reporter Gene Assay
EC50
21000±n/a nM
Citation
 Broo, A; Gottfries, J; Kossenjans, M; Lanna, L; Lindstedt-Alstermark, E; Nilsson, KA; Ohlsson, B; Thorstensson, M; Boije, M 2-substituted-3-phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease US Patent  US9181181 Publication Date 11/10/2015 
Target
Name:
Peroxisome proliferator-activated receptor alpha [169-468]
Synonyms:
NR1C1 | PPAR | PPARA | PPARA_HUMAN | Peroxisome proliferator-activated receptor alpha (PPAR alpha)
Type:
Enzyme
Mol. Mass.:
33974.77
Organism:
Homo sapiens (Human)
Description:
Q07869: amino acid 168-468
Residue:
300
Sequence:
NAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM190488
Synonyms:
US9181181, 36
Type:
Small organic molecule
Emp. Form.:
C26H26O6S
Mol. Mass.:
466.546
SMILES:
COc1ccc(CCOC(=O)Cc2ccc(SCc3ccccc3C(O)=O)cc2)cc1OC
Structure:
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