Reaction Details Report a problem with these data
Target
Trypsinogen 16
Ligand
BDBM193413
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
8±n/a
Temperature
298.15±n/a K
IC50
0.64±n/a nM
Comments
extracted
Citation
 Fujiyasu, J; Ohne, K; Yamaki, S; Imaizumi, T; Hondo, T; Matsuura, K; Satou, T; Sasamura, S Guanidinobenzoic acid compound US Patent  US9199927 Publication Date 12/1/2015 
Target
Name:
Trypsinogen 16
Synonyms:
Trypsin
Type:
Protein
Mol. Mass.:
26127.36
Organism:
Mus musculus (Mouse)
Description:
Q9Z1R9
Residue:
246
Sequence:
MSALLFLALVGAAVAFPVDDDDKIVGGYTCRENSVPYQVSLNSGYHFCGGSLINDQWVVSAAHCYKTRIQVRLGEHNINVLEGNEQFIDAAKIIKHPNFNRKTLNNDIMLIKLSSPVTLNARVATVALPSSCAPAGTQCLISGWGNTLSFGVSEPDLLQCLDAPLLPQADCEASYPGKITGNMVCAGFLEGGKDSCQGDSGGPVVCNGELQGIVSWGYGCALPDNPGVYTKVCNYVDWIQDTIAAN
  
Inhibitor
Name:
BDBM193413
Synonyms:
US9199927, 95
Type:
Small organic molecule
Emp. Form.:
C29H29ClN4O8
Mol. Mass.:
597.016
SMILES:
CC(C)(Oc1ccc(C[C@@H](NC(=O)Cc2ccc(OC(=O)c3ccc(NC(N)=N)cc3)cc2Cl)C(O)=O)cc1)C(O)=O |r|
Structure:
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