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Target
Tyrosine-protein kinase transforming protein Src [144-247,E177R,S178L,E179Q,T180R,T181V,C186A,K201L]
Ligand
BDBM195583
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
pH
7.35±n/a
Kd
2.5±0.6 nM
Comments
extracted
Citation
 Ju, T; Niu, W; Guo, J Evolution of Src Homology 2 (SH2) Domain to Recognize Sulfotyrosine. ACS Chem Biol 11:2551-7 (2016) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase transforming protein Src [144-247,E177R,S178L,E179Q,T180R,T181V,C186A,K201L]
Synonyms:
SRC_RSVSE | Src homology 2 domain mutant (E36R/S37L/E38Q/T39R/T40V/C45A/K60L) | Src homology 2 domain mutant (SH2-60.1) | V-SRC
Type:
Protein
Mol. Mass.:
12019.10
Organism:
Rous sarcoma virus (Virus)
Description:
P63185[144-247,E177R,S178L,E179Q,T180R,T181V,C186A,K201L]
Residue:
104
Sequence:
QAEEWYFGKITRRESERLLLNPENPRGTFLVRRLQRVKGAYALSVSDFDNAKGLNVLHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
  
Inhibitor
Name:
BDBM195583
Synonyms:
Phosphotyrosine (pTyr)
Type:
Small organic molecule
Emp. Form.:
C9H10NO6P
Mol. Mass.:
259.1537
SMILES:
[NH3+][C@@H](Cc1ccc(OP([O-])([O-])=O)cc1)C([O-])=O |r|
Structure:
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